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However, long-term use can lead to significant side effects, including: Disrupted gut health
REDEFINE 1 (obesity, no diabetes) A phase 3a, 68-week, multicentre, double-blind, placebo- and active-controlled trial (NCT05567796 [10] ) enrolling 3,417 adults without diabetes with BMI 30, or 27 with at least one obesity-related complication
It is intentional, not pathological, and reversible
10.3390/nu13093238 Nutrients
4Gently swirl or roll the vial until the powder is completely dissolved and the solution is clear
On the other hand, Aviles-Olmos 2013 only included patients who had PD for more than 5 years [28]
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